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Roflumilast N-oxide
CAS No. 292135-78-5
Roflumilast N-oxide ( Roflumilast N-oxide )
Catalog No. M18375 CAS No. 292135-78-5
Roflumilast N-oxide is a PDE type 4 inhibitor.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 40 | In Stock |
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| 5MG | 61 | In Stock |
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| 10MG | 91 | In Stock |
|
| 25MG | 156 | In Stock |
|
| 50MG | 259 | In Stock |
|
| 100MG | 332 | In Stock |
|
| 500MG | 797 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRoflumilast N-oxide
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NoteResearch use only, not for human use.
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Brief DescriptionRoflumilast N-oxide is a PDE type 4 inhibitor.
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DescriptionRoflumilast N-oxide is a phosphodiesterase 4 inhibitor. Roflumilast N-oxide is the active metabolite of roflumilast. Roflumilast N-Oxide in Combination with Formoterol Enhances the Antiinflammatory Effect of Dexamethasone in Airway Smooth Muscle Cells. Roflumilast n-oxide associated with PGE2 prevents the neutrophil elastase-induced production of chemokines by epithelial cells.
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SynonymsRoflumilast N-oxide
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PathwayChromatin/Epigenetic
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TargetCOX
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RecptorPDE4
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Research Area——
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Indication——
Chemical Information
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CAS Number292135-78-5
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Formula Weight419.21
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Molecular FormulaC17H14Cl2F2N2O4
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Purity98%
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SolubilityDMSO : 320 mg/mL 763.34 mM;
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SMILESClc3c[n+]([O-])cc(Cl)c3NC(=O)c2ccc(OC(F)F)c(OCC1CC1)c2
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Chemical NameN-(3,5-Dichloro-1-oxopyridin-4-yl)-4-difluoromethoxy-3-cyclopropylmethoxybenzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Victoni T,etal.Roflumilast n-oxide associated with PGE2 prevents the neutrophil elastase-induced production of chemokines by epithelial cells.Int Immunopharmacol. 2016 Jan;30:1-8.
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